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Mixture of MMP-2, MLC, and NOS Inhibitors Affects NO Metabolism and Protects Heart from Cardiac I/R Injury
OBJECTIVES: Coronary reperfusion procedure leads to ischemia/reperfusion injury of the heart (IRI). IRI arises from increased degradation of myosin light chains and increased activity of matrix metalloproteinase 2 (MMP-2). Increased production of toxic peroxynitrite (ONOO(−)) during oxidative stress...
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| Publié dans: | Cardiol Res Pract |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Hindawi
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7166281/ https://ncbi.nlm.nih.gov/pubmed/32322413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/1561478 |
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