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Cardioprotective effect of MMP‐2‐inhibitor‐NO‐donor hybrid against ischaemia/reperfusion injury

Hypoxic injury of cardiovascular system is one of the most frequent complications following ischaemia. Heart injury arises from increased degradation of contractile proteins, such as myosin light chains (MLCs) and troponin I by matrix metalloproteinase 2 (MMP‐2). The aim of the current research was...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Krzywonos‐Zawadzka, Anna, Franczak, Aleksandra, Olejnik, Agnieszka, Radomski, Marek, Gilmer, John F., Sawicki, Grzegorz, Woźniak, Mieczysław, Bil‐Lula, Iwona
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433672/
https://ncbi.nlm.nih.gov/pubmed/30729745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14191
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