Mixture of MMP-2, MLC, and NOS Inhibitors Affects NO Metabolism and Protects Heart from Cardiac I/R Injury

OBJECTIVES: Coronary reperfusion procedure leads to ischemia/reperfusion injury of the heart (IRI). IRI arises from increased degradation of myosin light chains and increased activity of matrix metalloproteinase 2 (MMP-2). Increased production of toxic peroxynitrite (ONOO(−)) during oxidative stress...

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Foilsithe in:Cardiol Res Pract
Main Authors: Krzywonos-Zawadzka, Anna, Franczak, Aleksandra, Sawicki, Grzegorz, Bil-Lula, Iwona
Formáid: Artigo
Teanga:Inglês
Foilsithe: Hindawi 2020
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7166281/
https://ncbi.nlm.nih.gov/pubmed/32322413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/1561478
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