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Fremanezumab and its isotype slow propagation rate and shorten cortical recovery period but do not prevent occurrence of cortical spreading depression in rats with compromised blood brain barrier
Most centrally-acting migraine preventive drugs suppress frequency and velocity of cortical spreading depression (CSD). The purpose of the current study was to determine how the new class of peripherally acting migraine preventive drug (i.e., the anti-CGRP-mAbs) affect CSD – an established animal mo...
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| Publicat a: | Pain |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7166155/ https://ncbi.nlm.nih.gov/pubmed/31895266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001791 |
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