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Fremanezumab and its isotype slow propagation rate and shorten cortical recovery period but do not prevent occurrence of cortical spreading depression in rats with compromised blood brain barrier

Most centrally-acting migraine preventive drugs suppress frequency and velocity of cortical spreading depression (CSD). The purpose of the current study was to determine how the new class of peripherally acting migraine preventive drug (i.e., the anti-CGRP-mAbs) affect CSD – an established animal mo...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Pain
Päätekijät: Melo-Carrillo, Agustin, Schain, Aaron J., Stratton, Jennifer, Strassman, Andrew M., Burstein, Rami
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7166155/
https://ncbi.nlm.nih.gov/pubmed/31895266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001791
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