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Sequence and chromatin determinants of transcription factor binding and the establishment of cell type-specific binding patterns

Transcription factors (TFs) selectively bind distinct sets of sites in different cell types. Such cell type-specific binding specificity is expected to result from interplay between the TF’s intrinsic sequence preferences, cooperative interactions with other regulatory proteins, and cell type-specif...

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Veröffentlicht in:Biochim Biophys Acta Gene Regul Mech
Hauptverfasser: Srivastava, Divyanshi, Mahony, Shaun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7166147/
https://ncbi.nlm.nih.gov/pubmed/31639474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2019.194443
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