Nonclassical nuclear localization signals mediate nuclear import of CIRBP

The specific interaction of importins with nuclear localization signals (NLSs) of cargo proteins not only mediates nuclear import but also, prevents their aberrant phase separation and stress granule recruitment in the cytoplasm. The importin Transportin-1 (TNPO1) plays a key role in the (patho-)phy...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bourgeois, Benjamin, Hutten, Saskia, Gottschalk, Benjamin, Hofweber, Mario, Richter, Gesa, Sternat, Julia, Abou-Ajram, Claudia, Göbl, Christoph, Leitinger, Gerd, Graier, Wolfgang F., Dormann, Dorothee, Madl, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7165476/
https://ncbi.nlm.nih.gov/pubmed/32234784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1918944117
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