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Unraveling the iterative type I polyketide synthases hidden in Streptomyces

Type I polyketide synthases (T1PKSs) are one of the most extensively studied PKSs, which can act either iteratively or via an assembly-line mechanism. Domains in the T1PKSs can readily be predicted by computational tools based on their highly conserved sequences. However, to distinguish between iter...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Wang, Bin, Guo, Fang, Huang, Chunshuai, Zhao, Huimin
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7165468/
https://ncbi.nlm.nih.gov/pubmed/32217738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1917664117
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