Synthetic molecular evolution of host cell-compatible, antimicrobial peptides effective against drug-resistant, biofilm-forming bacteria

Novel classes of antibiotics and new strategies to prevent and treat infections are urgently needed because the rapid rise in drug-resistant bacterial infections in recent decades has been accompanied by a parallel decline in development of new antibiotics. Membrane permeabilizing antimicrobial pept...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Starr, Charles G., Ghimire, Jenisha, Guha, Shantanu, Hoffmann, Joseph P., Wang, Yihui, Sun, Leisheng, Landreneau, Brooke N., Kolansky, Zachary D., Kilanowski-Doroh, Isabella M., Sammarco, Mimi C., Morici, Lisa A., Wimley, William C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7165445/
https://ncbi.nlm.nih.gov/pubmed/32241895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1918427117
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