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Increasing Mitochondrial ATP Synthesis with Butyrate Normalizes ADP and Contractile Function in Metabolic Heart Disease

Metabolic heart disease (MHD), which is strongly associated with heart failure with preserved ejection fraction (HFpEF), is characterized by reduced mitochondrial energy production and contractile performance. In this study, we tested the hypothesis that an acute increase in ATP synthesis, via short...

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Detalhes bibliográficos
Publicado no:NMR Biomed
Main Authors: Panagia, Marcello, He, Huamei, Baka, Tomas, Pimentel, David R., Croteau, Dominique, Bachschmid, Markus M., Balschi, James A., Colucci, Wilson S., Luptak, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7165026/
https://ncbi.nlm.nih.gov/pubmed/32066202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.4258
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