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Relative bioavailability of a pediatric dispersible tablet and adult film‐coated tablet of macitentan in healthy volunteers

To compare the pharmacokinetic (PK) properties of the pediatric dispersible tablet formulation of macitentan and the adult film‐coated tablet formulation of macitentan in healthy subjects. A randomized, open‐label, single‐dose, two‐sequence, two‐period, crossover, Phase 1 study was conducted in 12 h...

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Bibliografiske detaljer
Udgivet i:Pharmacol Res Perspect
Main Authors: Sidharta, Patricia N., Štěpánová, Radka, Globig, Susanne, Ulč, Ivan, Csonka, Dénes
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164404/
https://ncbi.nlm.nih.gov/pubmed/32302056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.580
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