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Relative bioavailability of a pediatric dispersible tablet and adult film‐coated tablet of macitentan in healthy volunteers

To compare the pharmacokinetic (PK) properties of the pediatric dispersible tablet formulation of macitentan and the adult film‐coated tablet formulation of macitentan in healthy subjects. A randomized, open‐label, single‐dose, two‐sequence, two‐period, crossover, Phase 1 study was conducted in 12 h...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Sidharta, Patricia N., Štěpánová, Radka, Globig, Susanne, Ulč, Ivan, Csonka, Dénes
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164404/
https://ncbi.nlm.nih.gov/pubmed/32302056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.580
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