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Variations in 5-methylcytosine and 5-hydroxymethylcytosine among human brain, blood, and saliva using oxBS and the Infinium MethylationEPIC array

Investigating 5-methylcytosine (5mC) has led to many hypotheses regarding molecular mechanism underlying human diseases and disorders. Many of these studies, however, utilize bisulfite conversion alone, which cannot distinguish 5mC from its recently discovered oxidative product, 5-hydroxymethylcytos...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biol Methods Protoc
Hauptverfasser: Gross, Jeffrey A., Lefebvre, François, Lutz, Pierre-Eric, Bacot, François, Vincent, Daniel, Bourque, Guillaume, Turecki, Gustavo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164292/
https://ncbi.nlm.nih.gov/pubmed/32328532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biomethods/bpw002
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