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Population pharmacokinetic modelling of busulfan and the influence of body composition in paediatric Fanconi anaemia patients
AIMS: Fanconi anaemia (FA) is a rare disorder characterized by progressive bone marrow failure that requires haematopoietic cell transplantation (HCT). Busulfan is used in conditioning regimens prior to HCT. Doses used in non‐FA patients cause life‐threatening toxicities in FA patients and data on b...
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| Pubblicato in: | Br J Clin Pharmacol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7163375/ https://ncbi.nlm.nih.gov/pubmed/31851762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14202 |
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