External validation of models for KIR2DS1/KIR3DL1-informed selection of hematopoietic cell donors fails

Several studies suggest that harnessing natural killer (NK) cell reactivity mediated through killer cell immunoglobulin-like receptors (KIRs) could reduce the risk of relapse after allogeneic hematopoietic cell transplantation. Based on one promising model, information on KIR2DS1 and KIR3DL1 and the...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Schetelig, Johannes, Baldauf, Henning, Heidenreich, Falk, Massalski, Carolin, Frank, Sandra, Sauter, Jürgen, Stelljes, Matthias, Ayuk, Francis Ayuketang, Bethge, Wolfgang A., Bug, Gesine, Klein, Stefan, Wendler, Sarah, Lange, Vinzenz, de Wreede, Liesbeth C., Fürst, Daniel, Kobbe, Guido, Ottinger, Hellmut D., Beelen, Dietrich W., Mytilineos, Joannis, Fleischhauer, Katharina, Schmidt, Alexander H., Bornhäuser, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Immunobiology and Immunotherapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162689/
https://ncbi.nlm.nih.gov/pubmed/31932846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019002887
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