Haplotype Motif-Based Models for KIR-Genotype Informed Selection of Hematopoietic Cell Donors Fail to Predict Outcome of Patients With Myelodysplastic Syndromes or Secondary Acute Myeloid Leukemia

Results from registry studies suggest that harnessing Natural Killer (NK) cell reactivity mediated through Killer cell Immunoglobulin-like Receptors (KIR) could reduce the risk of relapse after allogeneic Hematopoietic Cell Transplantation (HCT). Several competing models have been developed to class...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Schetelig, Johannes, Baldauf, Henning, Koster, Linda, Kuxhausen, Michelle, Heidenreich, Falk, de Wreede, Liesbeth C., Spellman, Stephen, van Gelder, Michel, Bruno, Benedetto, Onida, Francesco, Lange, Vinzenz, Massalski, Carolin, Potter, Victoria, Ljungman, Per, Schaap, Nicolaas, Hayden, Patrick, Lee, Stephanie J., Kröger, Nicolaus, Hsu, Kathy, Schmidt, Alexander H., Yakoub-Agha, Ibrahim, Robin, Marie
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7851088/
https://ncbi.nlm.nih.gov/pubmed/33542712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.584520
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