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Comprehensive Detection of Single Amino Acid Variants and Evaluation of Their Deleterious Potential in a PANC-1 Cell Line

Identifying single amino acid variants (SAAVs) in cancer is critical for precision oncology. Several advanced algorithms are now available to identify SAAVs, but attempts to combine different algorithms and optimize them on large data sets to achieve a more comprehensive coverage of SAAVs have not b...

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Publicado en:J Proteome Res
Autores principales: Tan, Zhijing, Zhu, Jianhui, Stemmer, Paul M., Sun, Liangliang, Yang, Zhichang, Schultz, Kendall, Gaffrey, Matthew J., Cesnik, Anthony J., Yi, Xinpei, Hao, Xiaohu, Shortreed, Michael R., Shi, Tujin, Lubman, David M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162681/
https://ncbi.nlm.nih.gov/pubmed/32058723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.9b00840
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