Cathepsin B Is Required for NLRP3 Inflammasome Activation in Macrophages, Through NLRP3 Interaction

The mechanisms leading to NOD-leucine rich repeat and pyrin containing protein 3 (NLRP3) inflammasome activation are still debated. It is well established that oligomerized NLRP3 interacts with apoptosis associated Speck-like protein containing a CARD domain (ASC) which polymerizes into filaments re...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Front Cell Dev Biol
Autori principali: Chevriaux, Angélique, Pilot, Thomas, Derangère, Valentin, Simonin, Harmonie, Martine, Pierre, Chalmin, Fanny, Ghiringhelli, François, Rébé, Cédric
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Cell and Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162607/
https://ncbi.nlm.nih.gov/pubmed/32328491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00167
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi