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HSP70 is a negative regulator of NLRP3 inflammasome activation
The NOD-leucine rich repeat and pyrin containing protein 3 (NLRP3) inflammasome is a multi-protein complex, aimed at producing IL-1β in response to danger signals which must be tightly regulated. Here we investigated the importance of the stress sensor, Heat Shock Protein 70 (HSP70) on NLRP3 inflamm...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6420651/ https://ncbi.nlm.nih.gov/pubmed/30874540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1491-7 |
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