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HSP70 is a negative regulator of NLRP3 inflammasome activation

The NOD-leucine rich repeat and pyrin containing protein 3 (NLRP3) inflammasome is a multi-protein complex, aimed at producing IL-1β in response to danger signals which must be tightly regulated. Here we investigated the importance of the stress sensor, Heat Shock Protein 70 (HSP70) on NLRP3 inflamm...

詳細記述

保存先:
書誌詳細
出版年:Cell Death Dis
主要な著者: Martine, Pierre, Chevriaux, Angélique, Derangère, Valentin, Apetoh, Lionel, Garrido, Carmen, Ghiringhelli, François, Rébé, Cédric
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420651/
https://ncbi.nlm.nih.gov/pubmed/30874540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1491-7
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