Synthesis and Antiviral Properties of Spirocyclic [1,2,3]‐Triazolooxazine Nucleosides

An efficient synthesis of spirocyclic triazolooxazine nucleosides is described. This was achieved by the conversion of β‐d‐psicofuranose to the corresponding azido‐derivative, followed by alkylation of the primary alcohol with a range of propargyl bromides, obtained by Sonogashira chemistry. The pro...

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Dettagli Bibliografici
Pubblicato in:Chemistry
Autori principali: Dell'Isola, Antonio, McLachlan, Matthew M. W., Neuman, Benjamin W., Al‐Mullah, Hawaa M. N., Binks, Alexander W. D., Elvidge, Warren, Shankland, Kenneth, Cobb, Alexander J. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: WILEY‐VCH Verlag 2014
Soggetti:
Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162048/
https://ncbi.nlm.nih.gov/pubmed/25082061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201403560
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