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Tenascin-C predicts poor outcomes for patients with colorectal cancer and drives cancer stemness via Hedgehog signaling pathway

BACKGROUND: Tenascin-C (TNC) is an extracellular matrix protein that is widely expressed in the stromal fibroblasts of various cancers. However, the roles of TNC in colorectal cancer (CRC) cells remain unclear. METHODS: The expression of TNC, cancer stem cell-like (CSC) and cell cycle markers, and H...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Yang, Zhaoting, Zhang, Chengye, Feng, Ying, Quan, Mingji, Cui, Yan, Xuan, Yanhua
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7161260/
https://ncbi.nlm.nih.gov/pubmed/32322169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-01188-w
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