Induction of aquaporin 4-reactive antibodies in Lewis rats immunized with aquaporin 4 mimotopes

Most cases of neuromyelitis optica spectrum disorders (NMOSD) harbor pathogenic autoantibodies against the water channel aquaporin 4 (AQP4). Binding of these antibodies to AQP4 on astrocytes initiates damage to these cells, which culminates in the formation of large tissue destructive lesions in the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Tsymala, Irina, Nigritinou, Magdalini, Zeka, Bleranda, Schulz, Rouven, Niederschick, Felix, Matković, Mia, Bauer, Isabel J., Szalay, Michael, Schanda, Kathrin, Lerch, Magdalena, Misu, Tatsuro, Fujihara, Kazuo, Bennett, Jeffrey L., Dahle, Charlotte, Pache, Florence, Rommer, Paulus, Leutmezer, Fritz, Illes, Zsolt, Leite, Maria Isabel, Palace, Jacqueline, Scholze, Petra, Reindl, Markus, Lassmann, Hans, Bradl, Monika
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160927/
https://ncbi.nlm.nih.gov/pubmed/32293546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-00920-x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados