Inflammasome Is Activated in the Liver of Cholestatic Patients and Aggravates Hepatic Injury in Bile Duct–Ligated Mouse

BACKGROUND & AIMS: Inflammation plays an important role in the pathogenesis of cholestatic liver injury, but it is unclear whether the inflammasome is involved and is the objective of this study. METHODS: Gene expression was analyzed in the livers of patients with primary biliary cholangitis (n ...

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Udgivet i:Cell Mol Gastroenterol Hepatol
Main Authors: Cai, Shi-Ying, Ge, Maoxu, Mennone, Albert, Hoque, Rafaz, Ouyang, Xinshou, Boyer, James L.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160576/
https://ncbi.nlm.nih.gov/pubmed/31887435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2019.12.008
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