Pathobiochemical signatures of cholestatic liver disease in bile duct ligated mice

BACKGROUND: Disrupted bile secretion leads to liver damage characterized by inflammation, fibrosis, eventually cirrhosis, and hepatocellular cancer. As obstructive cholestasis often progresses insidiously, markers for the diagnosis and staging of the disease are urgently needed. To this end, we comp...

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Detalhes bibliográficos
Publicado no:BMC Syst Biol
Main Authors: Abshagen, Kerstin, König, Matthias, Hoppe, Andreas, Müller, Isabell, Ebert, Matthias, Weng, Honglei, Holzhütter, Herrmann-Georg, Zanger, Ulrich M., Bode, Johannes, Vollmar, Brigitte, Thomas, Maria, Dooley, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654904/
https://ncbi.nlm.nih.gov/pubmed/26589287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-015-0229-0
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