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Hepatoprotection in bile duct ligated mice mediated by darbepoetin-α is not caused by changes in hepatobiliary transporter expression

Aims: Darbepoetin-α (DPO), a long-acting erythropoietin analog, has been shown to protect the liver against cholestatic injury, to exert an antifibrotic effect, and to increase the survival time in a model of common bile duct ligation. Here we evaluate whether these tissue-protective effects are cau...

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Main Authors: Eipel, Christian, Menschikow, Elena, Sigal, Michael, Kuhla, Angela, Abshagen, Kerstin, Vollmar, Brigitte
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515984/
https://ncbi.nlm.nih.gov/pubmed/23236546
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