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Hypoxia and the hypoxia inducible factor 1α activate protein kinase A by repressing RII beta subunit transcription
Overactivation of the cAMP signal transduction pathway plays a central role in the pathogenesis of endocrine tumors. Genetic aberrations leading to increased intracellular cAMP or directly affecting PKA subunit expression have been identified in inherited and sporadic endocrine tumors, but are rare...
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| 出版年: | Oncogene |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7160059/ https://ncbi.nlm.nih.gov/pubmed/32111982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-1223-6 |
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