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Actin Cytoskeleton and Focal Adhesions Regulate the Biased Migration of Breast Cancer Cells on Nanoscale Asymmetric Sawteeth

Physical guidance from the underlying matrix is a key regulator of cancer invasion and metastasis. We explore the effects of surface topography on the migration phenotype of multiple breast cancer cell lines using aligned nanoscale ridges and asymmetric sawtooth structures. Both benign and metastati...

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Publicat a:ACS Nano
Autors principals: Chen, Song, Hourwitz, Matt J., Campanello, Leonard, Fourkas, John T., Losert, Wolfgang, Parent, Carole A.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7159974/
https://ncbi.nlm.nih.gov/pubmed/30707556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.8b07140
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