Focal Adhesion Kinase Stabilizes the Cytoskeleton

Focal adhesion kinase (FAK) is a central focal adhesion protein that promotes focal adhesion turnover, but the role of FAK for cell mechanical stability is unknown. We measured the mechanical properties of wild-type (FAKwt), FAK-deficient (FAK−/−), FAK-silenced (siFAK), and siControl mouse embryonic...

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Autors principals: Fabry, Ben, Klemm, Anna H., Kienle, Sandra, Schäffer, Tilman E., Goldmann, Wolfgang H.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2011
Matèries:
Cellular Biophysics and Electrophysiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207160/
https://ncbi.nlm.nih.gov/pubmed/22067150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.09.043
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