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Asymmetric nanotopography biases cytoskeletal dynamics and promotes unidirectional cell guidance
Many biological and physiological processes depend upon directed migration of cells, which is typically mediated by chemical or physical gradients or by signal relay. Here we show that cells can be guided in a single preferred direction based solely on local asymmetries in nano/microtopography on su...
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Veröffentlicht in: | Proc Natl Acad Sci U S A |
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Hauptverfasser: | , , , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
National Academy of Sciences
2015
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4611618/ https://ncbi.nlm.nih.gov/pubmed/26417076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502970112 |
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