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Asymmetric nanotopography biases cytoskeletal dynamics and promotes unidirectional cell guidance

Many biological and physiological processes depend upon directed migration of cells, which is typically mediated by chemical or physical gradients or by signal relay. Here we show that cells can be guided in a single preferred direction based solely on local asymmetries in nano/microtopography on su...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sun, Xiaoyu, Driscoll, Meghan K., Guven, Can, Das, Satarupa, Parent, Carole A., Fourkas, John T., Losert, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611618/
https://ncbi.nlm.nih.gov/pubmed/26417076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502970112
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