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YAP Attenuates CD8 T Cell-Mediated Anti-tumor Response

YAP is a transcriptional coactivator of the Hippo signaling pathway that has largely been studied for its role in the regulation of organ size during development. Several studies have shown that YAP is upregulated in cancer cells, and more recently in the T regulatory (Treg) subset of CD4+ cells. Th...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Lebid, Andriana, Chung, Liam, Pardoll, Drew M., Pan, Fan
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158852/
https://ncbi.nlm.nih.gov/pubmed/32322254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00580
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