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YAP Attenuates CD8 T Cell-Mediated Anti-tumor Response

YAP is a transcriptional coactivator of the Hippo signaling pathway that has largely been studied for its role in the regulation of organ size during development. Several studies have shown that YAP is upregulated in cancer cells, and more recently in the T regulatory (Treg) subset of CD4+ cells. Th...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Lebid, Andriana, Chung, Liam, Pardoll, Drew M., Pan, Fan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158852/
https://ncbi.nlm.nih.gov/pubmed/32322254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00580
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