P2X1 Selective Antagonists Block HIV-1 Infection through Inhibition of Envelope Conformation-Dependent Fusion

Purinergic receptors are well-established modulators of inflammatory processes, primarily through detection of extracellular nucleotides that are released by dying or infected cells. Emerging literature has demonstrated that inhibition of these inflammatory receptors can block HIV-1 productive infec...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Soare, Alexandra Y., Malik, Hagerah S., Durham, Natasha D., Freeman, Tracey L., Alvarez, Raymond, Patel, Foramben, Satija, Namita, Upadhyay, Chitra, Hioe, Catarina E., Chen, Benjamin K., Swartz, Talia H.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158726/
https://ncbi.nlm.nih.gov/pubmed/31852781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01622-19
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