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HIV-1 Envelope Glycan Composition as a Key Determinant of Efficient Virus Transmission via DC-SIGN and Resistance to Inhibitory Lectins

The HIV-1 envelope (Env) surface is shrouded with an assortment of oligomannose-, hybrid-, and complex-type glycans that enable virus interaction with carbohydrate-recognizing lectins. This study examined the importance of glycan heterogeneity for HIV-1 transmission through the trans-infection pathw...

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Publicat a:iScience
Autors principals: Jan, Muzafar, Upadhyay, Chitra, Hioe, Catarina E.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6889591/
https://ncbi.nlm.nih.gov/pubmed/31704652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.10.030
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