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Alterations of HIV-1 envelope phenotype and antibody-mediated neutralization by signal peptide mutations
HIV-1 envelope glycoprotein (Env) mediates virus attachment and entry into the host cells. Like other membrane-bound and secreted proteins, HIV-1 Env contains at its N terminus a signal peptide (SP) that directs the nascent Env to the endoplasmic reticulum (ER) where Env synthesis and post-translati...
Enregistré dans:
| Publié dans: | PLoS Pathog |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5800646/ https://ncbi.nlm.nih.gov/pubmed/29370305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006812 |
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