Comparative Analysis of the Capsid Structures of AAVrh.10, AAVrh.39, and AAV8

Adeno-associated viruses (AAVs) from clade E are often used as vectors in gene delivery applications. This clade includes rhesus isolate 10 (AAVrh.10) and 39 (AAVrh.39) which, unlike representative AAV8, are capable of crossing the blood-brain barrier (BBB), thereby enabling the delivery of therapeu...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Mietzsch, Mario, Barnes, Candace, Hull, Joshua A., Chipman, Paul, Xie, Jun, Bhattacharya, Nilakshee, Sousa, Duncan, McKenna, Robert, Gao, Guangping, Agbandje-McKenna, Mavis
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2020
Aiheet:
Structure and Assembly
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158714/
https://ncbi.nlm.nih.gov/pubmed/31826994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01769-19
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