Connexin43 peptide, TAT-Cx43(266–283), selectively targets glioma cells, impairs malignant growth, and enhances survival in mouse models in vivo

BACKGROUND: Malignant gliomas are the most frequent primary brain tumors and remain among the most incurable cancers. Although the role of the gap junction protein, connexin43 (Cx43), has been deeply investigated in malignant gliomas, no compounds have been reported with the ability to recapitulate...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Jaraíz-Rodríguez, Myriam, Talaverón, Rocío, García-Vicente, Laura, Pelaz, Sara G, Domínguez-Prieto, Marta, Álvarez-Vázquez, Andrea, Flores-Hernández, Raquel, Sin, Wun Chey, Bechberger, John, Medina, José M, Naus, Christian C, Tabernero, Arantxa
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158688/
https://ncbi.nlm.nih.gov/pubmed/31883012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz243
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