Connexin43 peptide, TAT-Cx43(266–283), selectively targets glioma cells, impairs malignant growth, and enhances survival in mouse models in vivo

BACKGROUND: Malignant gliomas are the most frequent primary brain tumors and remain among the most incurable cancers. Although the role of the gap junction protein, connexin43 (Cx43), has been deeply investigated in malignant gliomas, no compounds have been reported with the ability to recapitulate...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Neuro Oncol
Asıl Yazarlar: Jaraíz-Rodríguez, Myriam, Talaverón, Rocío, García-Vicente, Laura, Pelaz, Sara G, Domínguez-Prieto, Marta, Álvarez-Vázquez, Andrea, Flores-Hernández, Raquel, Sin, Wun Chey, Bechberger, John, Medina, José M, Naus, Christian C, Tabernero, Arantxa
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2020
Konular:
Basic and Translational Investigations
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158688/
https://ncbi.nlm.nih.gov/pubmed/31883012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz243
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