Single-Dose, Intranasal Immunization with Recombinant Parainfluenza Virus 5 Expressing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike Protein Protects Mice from Fatal MERS-CoV Infection

Middle East respiratory syndrome coronavirus (MERS-CoV) can cause severe and fatal acute respiratory disease in humans and remains endemic in the Middle East since first being identified in 2012. There are currently no approved vaccines or therapies available for MERS-CoV. In this study, we evaluate...

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Detaylı Bibliyografya
Yayımlandı:mBio
Asıl Yazarlar: Li, Kun, Li, Zhuo, Wohlford-Lenane, Christine, Meyerholz, David K., Channappanavar, Rudragouda, An, Dong, Perlman, Stanley, McCray, Paul B., He, Biao
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7157776/
https://ncbi.nlm.nih.gov/pubmed/32265331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00554-20
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