Single intranasal immunization with chimpanzee adenovirus-based vaccine induces sustained and protective immunity against MERS-CoV infection

The recently identified Middle East Respiratory Syndrome Coronavirus (MERS-CoV) causes severe and fatal acute respiratory illness in humans. However, no approved prophylactic and therapeutic interventions are currently available. The MERS-CoV envelope spike protein serves as a crucial target for neu...

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Vydáno v:Emerg Microbes Infect
Hlavní autoři: Jia, Wenxu, Channappanavar, Rudragouda, Zhang, Chao, Li, Mingxi, Zhou, Haixia, Zhang, Shuyuan, Zhou, Panpan, Xu, Jiuyang, Shan, Sisi, Shi, Xuanling, Wang, Xinquan, Zhao, Jincun, Zhou, Dongming, Perlman, Stanley, Zhang, Linqi
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542157/
https://ncbi.nlm.nih.gov/pubmed/31130102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/22221751.2019.1620083
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