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Single-Dose, Intranasal Immunization with Recombinant Parainfluenza Virus 5 Expressing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike Protein Protects Mice from Fatal MERS-CoV Infection

Middle East respiratory syndrome coronavirus (MERS-CoV) can cause severe and fatal acute respiratory disease in humans and remains endemic in the Middle East since first being identified in 2012. There are currently no approved vaccines or therapies available for MERS-CoV. In this study, we evaluate...

詳細記述

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書誌詳細
出版年:mBio
主要な著者: Li, Kun, Li, Zhuo, Wohlford-Lenane, Christine, Meyerholz, David K., Channappanavar, Rudragouda, An, Dong, Perlman, Stanley, McCray, Paul B., He, Biao
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7157776/
https://ncbi.nlm.nih.gov/pubmed/32265331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00554-20
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