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Divergent Evolution of Legionella RCC1 Repeat Effectors Defines the Range of Ran GTPase Cycle Targets

Legionella pneumophila governs its interactions with host cells by secreting >300 different “effector” proteins. Some of these effectors contain eukaryotic domains such as the RCC1 (regulator of chromosome condensation 1) repeats promoting the activation of the small GTPase Ran. In this report, w...

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Publicado en:mBio
Main Authors: Swart, A. Leoni, Steiner, Bernhard, Gomez-Valero, Laura, Schütz, Sabina, Hannemann, Mandy, Janning, Petra, Irminger, Michael, Rothmeier, Eva, Buchrieser, Carmen, Itzen, Aymelt, Panse, Vikram Govind, Hilbi, Hubert
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7157520/
https://ncbi.nlm.nih.gov/pubmed/32209684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00405-20
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