Beyond Rab GTPases Legionella activates the small GTPase Ran to promote microtubule polymerization, pathogen vacuole motility, and infection

Legionella spp. are amoebae-resistant environmental bacteria that replicate in free-living protozoa in a distinct compartment, the Legionella-containing vacuole (LCV). Upon transmission of Legionella pneumophila to the lung, the pathogens employ an evolutionarily conserved mechanism to grow in LCVs...

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Vydáno v:Small GTPases
Hlavní autoři: Hilbi, Hubert, Rothmeier, Eva, Hoffmann, Christine, Harrison, Christopher F
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2014
Témata:
Commentary
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601303/
https://ncbi.nlm.nih.gov/pubmed/25496424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21541248.2014.972859
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