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Comparative Proteomics of Purified Pathogen Vacuoles Correlates Intracellular Replication of Legionella pneumophila with the Small GTPase Ras-related protein 1 (Rap1)

Legionella pneumophila is an opportunistic bacterial pathogen that causes a severe lung infection termed “Legionnaires' disease.” The pathogen replicates in environmental protozoa as well as in macrophages within a unique membrane-bound compartment, the Legionella-containing-vacuole (LCV). LCV...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Schmölders, Johanna, Manske, Christian, Otto, Andreas, Hoffmann, Christine, Steiner, Bernhard, Welin, Amanda, Becher, Dörte, Hilbi, Hubert
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383783/
https://ncbi.nlm.nih.gov/pubmed/28183814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M116.063453
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