Broad Protection of Pigs against Heterologous PRRSV Strains by a GP5-Mosaic DNA Vaccine Prime/GP5-Mosaic rVaccinia (VACV) Vaccine Boost

Background: Porcine reproductive and respiratory syndrome (PRRS) viruses are a major cause of disease and economic loss in pigs worldwide. High genetic diversity among PRRSV strains is problematic for successful disease control by vaccination. Mosaic DNA and vaccinia (VACV) vaccines were developed i...

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Bibliographische Detailangaben
Veröffentlicht in:Vaccines (Basel)
Hauptverfasser: Cui, Junru, O’Connell, Caitlin M., Hagen, Connor, Sawicki, Kim, Smyth, Joan A., Verardi, Paulo H., Van Kruiningen, Herbert J., Garmendia, Antonio E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7157218/
https://ncbi.nlm.nih.gov/pubmed/32121277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8010106
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