A PRRSV GP5-Mosaic vaccine: Protection of pigs from challenge and ex vivo detection of IFNγ responses against several genotype 2 strains

Porcine reproductive and respiratory syndrome virus (PRRSV), is a highly mutable RNA virus that affects swine worldwide and its control is very challenging due to its formidable heterogeneity in the field. In the present study, DNA vaccines constructed with PRRSV GP5-Mosaic sequences were complexed...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cui, Junru, O’Connell, Caitlin M., Costa, Antonio, Pan, Yan, Smyth, Joan A., Verardi, Paulo H., Burgess, Diane J., Van Kruiningen, Herbert J., Garmendia, Antonio E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6354972/
https://ncbi.nlm.nih.gov/pubmed/30703122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208801
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