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WIP1 promotes cancer stem cell properties by inhibiting p38 MAPK in NSCLC

Cancer stem cells (CSCs) are a small population of stem cell-like cancer cells that can initiate tumors in vivo, and are the major source of cancer initiation, relapse, and drug resistance. We previously reported that the p38 MAPK, through its downstream effectors MK2 and HSP27, suppressed CSC prope...

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Bibliografske podrobnosti
izdano v:Signal Transduct Target Ther
Main Authors: Deng, Kaiyuan, Liu, Liang, Tan, Xiaoming, Zhang, Zhen, Li, Jianjun, Ou, Yang, Wang, Xin, Yang, Shuang, Xiang, Rong, Sun, Peiqing
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156655/
https://ncbi.nlm.nih.gov/pubmed/32296033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-020-0126-x
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