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WIP1 promotes cancer stem cell properties by inhibiting p38 MAPK in NSCLC

Cancer stem cells (CSCs) are a small population of stem cell-like cancer cells that can initiate tumors in vivo, and are the major source of cancer initiation, relapse, and drug resistance. We previously reported that the p38 MAPK, through its downstream effectors MK2 and HSP27, suppressed CSC prope...

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Detalhes bibliográficos
Publicado no:Signal Transduct Target Ther
Main Authors: Deng, Kaiyuan, Liu, Liang, Tan, Xiaoming, Zhang, Zhen, Li, Jianjun, Ou, Yang, Wang, Xin, Yang, Shuang, Xiang, Rong, Sun, Peiqing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156655/
https://ncbi.nlm.nih.gov/pubmed/32296033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-020-0126-x
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