HSP90 Inhibitor Ganetespib (STA-9090) Inhibits Tumor Growth in c-Myc-Dependent Esophageal Squamous Cell Carcinoma

PURPOSE: Currently, the paucity of classical effective pharmacological drugs to treat esophageal squamous cell carcinoma (ESCC) is a major problem. The c-Myc (MYC) protein is a promising target as it is overexpressed in ESCC. MYC is a sensitive client protein of the heat shock protein 90 (HSP90) and...

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Bibliografiset tiedot
Julkaisussa:Onco Targets Ther
Päätekijät: Guan, Liuliu, Zou, Qingqing, Liu, Qian, Lin, Yiguang, Chen, Size
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Dove 2020
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Original Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156265/
https://ncbi.nlm.nih.gov/pubmed/32308431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S245813
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