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TRAF2 Ser-11 Phosphorylation Promotes Cytosolic Translocation of the CD40 Complex To Regulate Downstream Signaling Pathways

CD40 plays an important role in immune responses by activating the c-Jun N-terminal protein kinase (JNK) and NF-κB pathways; however, the precise mechanisms governing the spatiotemporal activation of these two signaling pathways are not fully understood. Here, using four different TRAF2-deficient ce...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Workman, Lauren M., Zhang, Laiqun, Fan, Yumei, Zhang, Weizhou, Habelhah, Hasem
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156217/
https://ncbi.nlm.nih.gov/pubmed/32041822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00429-19
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