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Molecular Mechanisms of Class B GPCR Activation: Insights from Adrenomedullin Receptors

[Image: see text] Adrenomedullin (AM) is a 52 amino acid peptide that plays a regulatory role in the vasculature. Receptors for AM comprise the class B G protein-coupled receptor, the calcitonin-like receptor (CLR), in complex with one of three receptor activity-modifying proteins (RAMPs). The C-ter...

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Publicado en:ACS Pharmacol Transl Sci
Main Authors: Garelja, Michael L., Au, Maggie, Brimble, Margaret A., Gingell, Joseph J., Hendrikse, Erica R., Lovell, Annie, Prodan, Nicole, Sexton, Patrick M., Siow, Andrew, Walker, Christopher S., Watkins, Harriet A., Williams, Geoffrey M., Wootten, Denise, Yang, Sung H., Harris, Paul W. R., Hay, Debbie L.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2020
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7155197/
https://ncbi.nlm.nih.gov/pubmed/32296766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00083
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